Overview of Selected Chemical Compounds and Intermediates

1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: That is an impurity related to bortezomib, a proteasome inhibitor used in the remedy of several myeloma. Its synthesis or examine is vital for ensuring the purity and protection with the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-7): A precursor within the synthesis of abiraterone acetate, a drug Employed in the remedy of prostate most cancers by inhibiting androgen generation.
Imatinib Intermediate (CAS NO. 152460-10-one): A critical compound inside the synthesis of imatinib, a drug that targets certain varieties of most cancers, which include Continual myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Employed in the synthesis of docetaxel, a chemotherapy medication that treats many cancers for example breast, lung, and prostate cancer.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): These are definitely intermediates within the synthesis of gemcitabine, an anti-most cancers drug. Their study is important for optimizing the creation course of action and Imatinib intermediate ensuring large purity.
Lapatinib Intermediate (CAS NO. 231278-eighty four-five): Lapatinib is utilized to deal with breast most cancers, and these intermediates are involved in its creation.
Fulvestrant Intermediates: Fulvestrant can be an estrogen receptor antagonist used in the treatment method of breast most cancers. Many intermediates help in the synthesis of this drug.
Paclitaxel Side Chain Acid (CAS NO. 949023-16-9): This intermediate is Utilized in the synthesis of paclitaxel, a chemotherapy drug productive in managing cancers such as ovarian, breast, and lung cancer.
three. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug used in the remedy of colorectal cancer and modest cell lung cancer.
3-Amino-1-hydroxyadamantane (CAS 702-82-9): This compound is linked to the synthesis of adamantane derivatives, which have a variety of apps, together with antiviral properties.
Vildagliptin Intermediates: CAS NO. 161599-46-8 Used in the production of vildagliptin, an oral drug for kind 2 diabetic issues that inhibits the enzyme DPP-four to control blood sugar concentrations.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-1): This compound is associated with the synthesis of various gluconic acid derivatives, which can be Utilized in foods, pharmaceutical, and industrial programs.
Canagliflozin Intermediate 2: A precursor from the synthesis of canagliflozin, a medication made use of to handle variety 2 diabetes by inhibiting sodium-glucose co-transporter 2 (SGLT2).

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